Search results for "Omphalotus olearius"

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Omphalotins E-I, Five Oxidatively Modified Nematicidal Cyclopeptides fromOmphalotus olearius

2009

Omphalotins E–I, oxidatively modified cyclic dodecapeptides, were isolated from mycelial extracts of the basidiomycete Omphalotus olearius, and their structures were determined by NMR spectroscopic and MS methods. Four of the five omphalotins contained an unprecedented N-hydroxylated tricyclic tryptophan derivative. All compounds exhibited strong and selective nematicidal activity against the plant pathogen Meloidogyne incognita with LD90 values between 2 and 5 μg mL–1. Cytotoxic activities were not detected up to 50 μg mL–1. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

chemistry.chemical_classificationOmphalotus oleariusbiologyStereochemistryChemical structureOrganic ChemistryTryptophanBasidiomycotaNuclear magnetic resonance spectroscopybiology.organism_classificationCyclic peptidechemistryMeloidogyne incognitaOrganic chemistryPhysical and Theoretical ChemistryMyceliumEuropean Journal of Organic Chemistry
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ChemInform Abstract: Omphalotins E-I, Five Oxidatively Modified Nematicidal Cyclopeptides from Omphalotus olearius.

2009

Omphalotins E–I, oxidatively modified cyclic dodecapeptides, were isolated from mycelial extracts of the basidiomycete Omphalotus olearius, and their structures were determined by NMR spectroscopic and MS methods. Four of the five omphalotins contained an unprecedented N-hydroxylated tricyclic tryptophan derivative. All compounds exhibited strong and selective nematicidal activity against the plant pathogen Meloidogyne incognita with LD90 values between 2 and 5 μg mL–1. Cytotoxic activities were not detected up to 50 μg mL–1. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

chemistry.chemical_classificationOmphalotus oleariusbiologyStereochemistryTryptophanGeneral Medicinebiology.organism_classificationAmino acidchemistry.chemical_compoundchemistryMeloidogyne incognitaPathogenMyceliumDerivative (chemistry)ChemInform
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